THE CIS-REGULATORY EFFECTS OF MODERN HUMAN-SPECIFIC VARIANTS

The cis-regulatory effects of modern human-specific variants

The Neanderthal and Denisovan genomes enabled the discovery of sequences that differ between modern and archaic humans, the majority of which are noncoding.However, our understanding of the regulatory consequences of these differences remains limited, in part due to the decay of regulatory marks in ancient samples.Here, Incense we used a massively

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MOLLUSCUM CONTAGIOSUM, DIAGNOSIS AND TREATMENT

Normal 0 false false Full Upholstered Bed false EN-US X-NONE X-NONE Molluscum contagiosum is a dermathology disease caused by molluscum contagiosum virus (MCV), pox viral group from Molluscipox viral genus.The incidence of molluscum contagiosum all over the world aprroximately 2% - 8% with prevalence 5% - 18% in HIV patient.Molluscum contagiosum se

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Global protein conjugation by ubiquitin-like-modifiers during ischemic stress is regulated by microRNAs and confers robust tolerance to ischemia.

Hibernation torpor provides an excellent model of natural tolerance to ischemia.We have previously shown that massive global SUMOylation occurs during hibernation torpor in ground squirrels.We have also shown that overexpression of Ubc9, SUMO-1, or SUMO-2/3 provides protection against ischemic damage in cell lines and cortical neurons exposed to ox

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